Cancer Therapy-Related Cardiac Dysfunction

By Anonymous -
Humanity from cancer has decreased enormously over the past few decades, in part, through earlier diagnosis and novel treatments. Appropriately, although cancer-free survival has increased, problems from cancer therapy, particularly effects of cardiac function have partial patient outcomes, impacting the overall morbidity and mortality . The National Cancer Institute (NCI) broadly defines cardiotoxicity as “toxicity that affects the heart”, and intends the Common Terminology Criteria for Hostile Events (CTCAE).Ewer and Lippman proposed cardiotoxicity based on the type and range of structural abnormalities and degree of reversibility.Type I is irreversible and dose-related with myocyte injury, whereas type II contains reversibility with cessation of treatment, absence of dose-relationship, and absence of ultrastructural abnormalities

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